Rockefeller University Research Assistant, Molecular Biology in New York, New York
Job Title Research Assistant, Molecular Biology
Laboratory / Department Laboratory of Molecular Biology
Research in the laboratory of molecular biology aims to identify the genes, circuits, cells, macromolecular assemblies and individual molecules that contribute to the function and dysfunction of the mammalian brain. Scientists in the laboratory of molecular biology have developed a suite of novel approaches based on the manipulation of bacterial artificial chromosomes (BACs) to investigate the histological and functional complexities of the mammalian brain in vivo and to understand how these mechanisms become dysfunctional in disease.
The Research Assistant will work on a project that will study the molecular basis of selective cellular vulnerability in Huntington's disease. Responsibilities include preparing human brain samples from donor tissue and using established profiling assays such as ATAC-Seq, bisulfite-Seq and Ox-bisulfite-Seq to elucidate the epigenetic properties of the DNA. Additional responsibilities include preparing genetic material for BeadChip methylation assays and trinucleotide repeat sizing. Will work with contract testing laboratories to ensure proper amounts of sample and control materials are sent.
Bachelor's degree in science required; educational emphasis in neuroscience or biology preferred. Previous experience with RNA isolation and in situ hybridization is a plus. Must have computer skills and familiarity with NCBI database tools. Must be organized, have excellent communication skills and keep clear accurate records.
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans